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For oral presentations, the first number is the Poster reference. Concurrent Session I: Immunology
Friday 7 September 2007, 09.00-10.30 Chairs: Bernhard Homey, Philippe Musette 002 [Oral 025]
Mast cell-derived endothelin-1 contributes to allergic inflammation
M Metz, B Schäfer, M Tsai, SJ Galli, M Maurer 003 [Oral 026]
Reduced systemic anaphylaxis and impaired mast cell degranulation in mice deficient in the K+ channel SK4
F Woelbing, E Shumilina, R Lam, M Sobiesiak, IM Zemtsova, H Mahmud, M Sausbier, P Ruth, F Lang, T Biedermann 004 [Oral 027]
A New Mouse Model for Mastocytosis
A. Roers, A Gerbaulet, J. Scholten, T Krieg, K Hartmann 005 [Oral 028]
TGF-beta/Smad3 -signaling regulates inflammatory responses in a murine model of contact hypersensitivity
A Lauerma, M Anthoni, N Fyhrquist-Vanni, H Wolff, H Alenius 006 [Oral 029]
TLR7-Agonists induce the expression of SOCSs genes in human Plasmacytoid Dendritic Cells
N Novak, WM Peng, L Maintz, C Bussmann, JP Allam, CF Yu 007 [Oral 030]
UV-induced regulatory T cells inhibit antigen-presenting cells via by-stander suppression.
A Schwarz, A Maeda, T Schwarz 008 [Oral 031]
Beta endorphin produced by tumor cells plays a role in immune escape
B Duthey, E Deak, K Hardt, S Hoehl, D.S Schadendorf, WH Boehncke 009 [Oral 032]
Antimicrobially active hornerin peptides as protective factors of healthy skin
ZH Wu, U Meyer-Hoffert, J Bartels, YH He, J Harder, J-M Schröder 010 [Oral 033]
Phenotypic and Functional Characterization of Circulating CD4 T Lymphocytes Expressing the Glyscosylphosphatidylinositol-anchored CD160 Receptor
V Schiavon, N Ortonne, C Schmitt, M Bagot, A Bensussan Concurrent Session II: Clinical Investigation and Epidemiology
Friday 7 September 2007, 09.00-10.30 Chairs: Jean-Claude Roujeau, Hywel Williams 162 [Oral 034]
The Effect of PageRank Adjustment on Dermatology Journal Impact Factor
RP Dellavalle, LM Schilling, MA Rodriguez, H Van de Sompel, J Bollen 163 [Oral 035]
Cumulative incidence of skin cancer in Simultaneous Pancreas Kidney transplant recipients and the role of immunosuppressive therapy
HC Wisgerhof, PJM Van der Boog, HJW De Fijter, R Willemze, JN Bouwes Bavinck 085 [Oral 036]
Efficacy of low-calorie diet associated to suboptimal cyclosporine in the treatment of severe chronic plaque psoriasis of obese patients: open, controlled, randomized clinical trial
P Gisondi, F Adami, V Di Francesco, M Zamboni, G Girolomoni 086 [Oral 037]
Completion of a pharmacogenetic screen of the methotrexate metabolic pathway
B Warren, RL Smith, E Campalani, C Smith, JN Barker, J Worthington, CEM Griffiths 087 [Oral 038]
CT327: a novel topical treatment of psoriasis and dermatitis
L Bertarione Rava Rossa, S Traversa, V Mainero, D Barone, C Oderda, S Fumero, C Pincelli, A Marconi 147 [Oral 039]
In vivo Confocal Laser Scanning Microscopy of Equivocal Pigmented Skin Lesions
R Hofmann-Wellenhof, V Ahlgrimm-Siess, R Fink-Puches, E Richtig, IH Wolf, A Gerger, J Smolle, H Kerl 164 [Oral 040]
Critical review of generic and dermatology specific health related quality of life instruments
T Nijsten, H Both, JJ Busschbach, ML Essink-Bot 165 [Oral 041]
The association between skin prick tests for house dust mite and atopic dermatitis differs between boys and girls in Ghana
JN Bouwes Bavinck, AA Hogewoning, S Lavrijsen, M Yazdanbakhsh, Y Aryetey, I Akosua Larbi, AS Amoah, D Boakye 166 [Oral 042]
The Prevalence of Papulopustular Rosacea and Relationship to Cutaneous Photodamage
M McAleer, P Fitzpatrick, FC Powell Concurrent Session III: Cell Adhesion, Matrix Biology and Growth Factors
Friday 7 September 2007, 09.00-10.30 Chairs: Thomas Krieg, Ulpu Saarialho-Kere 211 [Oral 043]
Epidermal Insulin and IGF-1 signaling cooperatively regulate skin morphogenesis and homeostasis
CM Niessen, H Ibrahim, L Koch, H Lübken, C Wickenhauser, JC Brüning 212 [Oral 044]
Kindlin-1 regulates proliferation, polarity and motility of epidermal keratinocytes through EGF- and integrin-mediated signaling pathways
CB Herz, MJ Recknagel, L Bruckner-Tuderman, C Has 179 [Oral 045]
The EBS K14 R125P mutation induces the down-regulation of intercellular adhesion components
M Liovic, M D'Alessandro, M Tomic-Canic, V Bolshakov, EB Lane 180 [Oral 046]
The association of plectin (PL) with various intermediate filament (IF) proteins is regulated by phosphorylation of a serine residue in its COOH-terminal extremity
L Fontao, L Borradori, Y Schneider, F Jaunin 181 [Oral 047]
The neonatal Fc receptor promotes tissue injury in experimental epidermolysis bullosa acquisita
A Sesarman, AG Sitaru, FO Olaru, D Zillikens, C Sitaru 182 [Oral 048]
Role of ADAM-9 disintegrin-cysteine rich domains for keratinocyte migration
P Zigrino, J Steiger, JW Fox, A Schild, R Nischt, C Mauch 183 [Oral 049]
Fibronectin regulates the assembly of Latent TGF-beta Binding Protein 4, LTBP-4 into the extracellular matrix
A Kantola, J Keski-Oja, K Koli 184 [Oral 050]
Extracellular heat shock protein-90alpha: linking hypoxia to skin cell motility and wound healing
S Guan, M Chen, DT Woodley, W Li 185 [Oral 051]
Ablation of Integrin-Linked Kinase in Fibroblasts: Altered Mechanical Properties Resulting in Disturbed Wound Healing
B Eckes, MC Zweers, A Peters, CP Denton, R Fässler, T Krieg Concurrent Session IV: Photobiology, Pigmentation and Melanoma
Friday 7 September 2007, 09.00-10.30 Chairs: Neil Gibbs, Peter Wolf 245 [Oral 052]
Survivin modulates cell cycle and interferes with UV-induced apoptosis in human keratinocytes
K Dallaglio, A Marconi, M Dumas, F Bonté, R Lotti, F Truzzi, C Gemelli, C Pincelli 246 [Oral 053]
In Graft versus Host disease Extracorporeal Photopheresis increases number and function of regulatory T cells
S Schmitt, K Mahnke, K. Schönfeld, S Karakhanova, AH Enk
247 [Oral 054]
Ultraviolet radiation exposure accelerates the accumulation of the aging-dependent T414G mitochondrial DNA mutation in human skin
MA Birch-Machin, J Birket 248 [Oral 055]
Immunosuppressive Effects of Psoralen Photochemotherapy and Photodynamic Therapy May be Realized Through Production of Photosensitizer Photooxidation Products
A Kyaqgova, L Kozir, G Mansurova, I Moshnina, E Kozhinova, V Ponomarev, A Potapenko 249 [Oral 056]
Reduced Antigen-Presenting Ability of Bone Marrow-Derived Dendritic Cells from Ultraviolet-B-Irradiated or Hapten-Painted Mice
S Gorman, J Lee, H Hart 287 [Oral 057]
Genome-wide RNAi-Screen Identifies Novel Regulators of Melanin Secretion
AK Ganesan, H Ho, MA White 288 [Oral 058]
In vitro and in vivo studies of proliferative and invasive signature melanoma cells
O Eichhoff, NC Schlegel, U Döbbeling, S Hemmi, R Dummer, KS Hoek 289 [Oral 059]
Beta-catenin induces immortalisation of melanocytes by suppressing p16INK4a expression and co-operates with N-Ras in melanoma development
V Delmas, F Beermann, S Martinozzi, S Carreira, J Ackermann, M Kumasaka, L Denat, J Goodall, F Luciani, A Viros, N Demirkan, BC Bastian, CR Goding, L Larue 290 [Oral 060]
Phosphodiesterases mediate cross-talk between the cAMP and the RAS/RAF/MEK/ERK pathways in melanoma
N Dumaz, A Marquette, M Bagot, A Bensussan Concurrent Session V: Epidermis and Hair Structure and Function
Saturday 8 September, 11.00-12.30 Chairs: Cornelia Mauch, Andrey Panteleyev 379 [Oral 061]
TAK1 regulates hair follicle development in EDA receptor signaling
K Sayama, K Kajiya, Y Shirakata, Y Hanakawa, S Hirakawa, S Akira, J Kishimoto, K Hashimoto 325 [Oral 062]
Two models for isolation to study Merkel cells
N Boulais, U Péreira, N Lebonvallet, G Dorange, N Rougier, C Chesne, L Misery 326 [Oral 063]
Interfollicular Keratinocyte Stem Cell Mapping by Multi-Epitope Ligand Cartography (MELC) Reveales the Existence of Two Subpopulations
R Böckelmann, AJ Pommer, H Hofmeister, L Philipsen, H Gollnick, B Bonnekoh 327 [Oral 064]
Topical Hyaluronate Fragments Prevent Corticosteroid-Induced Skin Atrophy in Mouse Without Interfering with Anti-Inflammatory Effect
G Kaya, C Tran, O Sorg, D Grand, R Hotz, P Carraux, JH Saurat 328 [Oral 065]
Restin is associated with epidermal lamellar bodies
A-A Raymond, A Gonzalez de Peredo, A Stella, G Serre, B Monsarrat, M Simon 329 [Oral 066]
Identification and characterization of three new putative lipases specifically expressed in granular keratinocytes
E Toulza, N Mattiuzzo, M-F Galliano, N Jonca, C Dossat, D Jacob, A De Daruvar, P Wincker, G Serre, M Guerrin 330 [Oral 067]
Expression of aquaporins in human skin keratinocytes: relationship to differentiation
JMV Verbavatz, M Boury-Jamot, J-H Cauchard, JE Daraspe, E Noblesse, K Lezou, M Dumas 331 [Oral 068]
Purification and Characterization of Vaspin in human skin - a new epidermal serine protease inhibitor
U Meyer-Hoffert, Z Wu, E Ziernig, RS Sreseli, J Bartels, J-M Schröder 332 [Oral 069]
Caspase-14 protects against epidermal UVB photo-damage and water loss
G Denecker, E Hoste, B Gilbert, T Hochepied, P Ovaere, S Lippens, C Van den Broucke, P Van Damme, K D'Herde, JP Hachem, G Borgonie, R Presland, L Schoonjans, C Libert, J Vandekerckhove, K Gevaert, P Vandenabeele, W Declercq Concurrent Session VI: Auto-Immunity, Inflammation and Infectious Diseases
Saturday 8 September, 11.00-12.30 Chairs: Robert Gniadecki, Vincent Piguet 394 [Oral 070]
Genetic characterization of human Dsg3-specific B cells isolated by flow cytometry from peripheral blood of patients with pemphigus vulgaris
J Yamagami, H Takahashi, T Ota, M Amagai 395 [Oral 071]
Suppressive effects of CD4+ CD25+ regulatory T cells on the development of phenotypes in a mouse model of pemphigus vulgaris
T Yokoyama, S Matsuda, Y Takae, M Amagai, S Koyasu 396 [Oral 072]
Characterization of autoreactive B cell response to BP230 and identification of an immunodominant region targeted by bullous pemphigoid autoantibodies
V Calabresi, L Borradori, G Zambruno, G Di Zenzo 397 [Oral 073]
T and B cell responses targeting distinct regions of the non-collagenous domain 1 (NC1) of Collagen VII correlate with the clinical activity of EBA
RM Müller, C Dahler, C Möbs, E Wenzel, CM Veldman, G Messer, SC Hofmann, M Hertl, A Niedermeier 445 [Oral 074]
Epigenetic control of CD14 and antimicrobial peptide cathelicidin in keratinocytes by histone acetylation
JS Schauber, YO Oda, A Büchau, AS Steinmeyer, U Zügel, D Bikle, R Gallo 446 [Oral 075]
Experimental disruption of the human skin barrier results in enhanced secretion of the antimicrobial proteins Psoriasin (S100A7) and RNase 7
R Gläser, J Harder, B Köten, H Lange, E Proksch, M Weichenthal, J-M Schröder 398 [Oral 076]
Possible involvement of mast cells in the pathogenesis of xanthoma and atherosclerosis upon stimulation with oxidized low-density lipoprotein
M Matsumoto, K Wada, M Kurokawa, M Ikeda, R Kamijima, H Kodama, S Sano 399 [Oral 077]
A crucial role of inflammatory caspase-1 in non-classical protein secretion from fibroblasts and keratinocytes
M Keller, A Rüegg, S Werner, HD Beer 447 [Oral 078]
HPV26 and HPV88 infections are carcinogenic in immunosuppression causing squamous cell carcinoma of the nail unit
A Handisurya, J Kullander, O Forslund, A Rieger, A Bankier, A Koller, A Salat, G Stingl, J Dillner, R Kirnbauer Concurrent Session VII: Genetic Disease, Gene Expression and Gene Therapy
Saturday 8 September 2007, 14.30-16.00 Chairs: Maurice van Steensel, Giovanna Zambruno 464 [Oral 079]
Biochemical association between kindlin-1, kindlin-2 and migfilin and relevance to Kindler syndrome
JE Lai-Cheong, S Ussar, K Arita, I Hart, JA McGrath 465 [Oral 080]
Chronic colitis due to epithelial barrier defect: role of kindlin-1 isoforms
JS Kern, CB Herz, E Haan, L Bruckner-Tuderman, C Has 466 [Oral 081]
Rescue of lethal dystrophic epidermolysis bullosa model mice by corrective COL7A1 gene transfer
K Ito, D Sawamura, W Nishie, H Nakamura, M Goto, A Shibaki, J Uitto, M Akiyama, H Shimizu 467 [Oral 082]
The collagen VII hypomorph, a viable mouse model for dystrophic epidermolysis bullosa, allows testing of molecular therapies
A Fritsch, S Loeckermann, JS Kern, R Fässler, L Bruckner-Tuderman 468 [Oral 083]
Harmless selection of genetically manipulated human stem keratinocytes
T Magnaldo, V Bergoglio, E Warrick, F Larcher, O Chevallier, M DelRio 469 [Oral 084]
Functional model systems for congenital ichthyosis: Basic and long way to therapy
KM Eckl, S Torres, S Juanes, D Metze, P Krieg, H-C Hennies 470 [Oral 085]
The interferon-inducible, anti-apoptotic G1P3 protein is under the control of the non-coding RNA, PRINS and is highly upregulated in psoriasis
K Szegedi, E. Sonkoly, Zs. B. Bata-Csörgo, I. Németh, A Dobozy, L Kemény, M Széll 471 [Oral 086]
Early onset psoriasis is associated with SNPs in the PTPN22 region
RL Smith, RB Warren, S Eyre, X Ke, HS Young, M Allen, JN Barker, CEM Griffiths, J Worthington 472 [Oral 087]
Association analysis of the IL12B and IL23R genes in clinical variants of psoriasis
JN Barker, RC Trembath, F Capon, C Dunster, M Allen, FO Nestle, AD Burden, J Worthington, CEM Griffiths Concurrent Session VIII: Carcinogenesis and Angiogenesis
Saturday 8 September 2007, 14.30-16.00 Chairs: Veli-Matti Kähäri, tba 535 [Oral 088]
Development of a 3D tissue culture model of human skin carcinoma
S Commandeur, R Siamari, JN Bouwes Bavinck, FR De Gruijl, CP Tensen, A El Ghalbzouri 536 [Oral 089]
A processed laminin-332 domain selectively localizes to and potentiates carcinoma development
MM Tran, PR Rousselle, NP Nokelainen, S Talapragada, NN Nguyen, MP Marinkovich 537 [Oral 090]
Tissue Microarray Based Analysis of MMP-7, CD44v3 and HB-EGF in Recessive Dystrophic Epidermolysis Bullosa-associated and Sporadic Squamous Cell Carcinomas
A Kivisaari, M Kallajoki, JA McGrath, JW Bauer, F Weber, R Königová, M Csikós-Medvecz, H Shimizu, D Sawamura, KC Sato-Matsumura, K Sinemus, W Beckert, V-M Kähäri 538 [Oral 091]
IKKa is a tumor suppressor in stratified epithelia as a component of the TGFβ anti-proliferative pathway
A Costanzo, F Moretti, B Marinari, ML Giustizieri, A Giunta, C Ballaro, M Papoutsaki, S Alema, S Chimenti 539 [Oral 092]
Transgenic expression of Noggin promotes skin tumorigenesis via stimulation of Sonic Hedgehog signaling pathway
AN Mardaryev, AA Sharov, T Sharova, M Grachtchouk, HR Byers, R Atoyan, A.V. Sargsyan, P.A. Overbeek, AA Dlugosz, VA Botchkarev 518 [Oral 093]
Placental cells increase angiogenesis during skin wound healing
K Khosrotehrani, C Droitcourt, E Mathieu, M Oster, S Aractingi 519 [Oral 094]
Non Invasive in vivo Measurement of Hypoxia-induced Angiogenesis in Contact Hypersensitivity Reactions (CHSR) using 18F-Fluoroazomycin Arabinosid (FAZA) and Positron Emission Tomography (PET)
M Kneilling, B Pichler, G Reischl, R Mailhammer, A Yazdi, D Bukala, F Cay, C Widmer, C Reitmeier, M Judenhofer, C Claussen, HJ Machulla, M Röcken
540 [Oral 095]
Senescence driven by reactive oxygen species (ROS) via NF-kappa B suppresses UVB-induced skin photocarcinogenesis
AL Kim, JH Back, Y Zhu, M Athar, X Tang, L Kopelovich, DR Bickers 541 [Oral 096]
Combining ER-stress inducing agents with protein disulphide inhibitors as a novel therapeutic strategy for metastatic melanoma
P Lovat, CPF Redfern, MA Birch-Machin
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